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Effects of IFN-γ neutralization on the re-sensitized drug response induced by CIK
| IC50 (µM) | Resistance index | Resistance reversal index | |
|---|---|---|---|
| A549 | 5±1.25 | ||
| A549/DDP | 74.5±5.24 | 14.9 | |
| A549/DDP co-cultured for 20h | 15.6±2.89* | 3.12 | 4.77 |
| 1μg/mL anti-IFN-γ antibody | 63.97±3.07 | 12.79 | 1.16 |
| 5μg/mL anti-IFN-γ antibody | 60.26±4.42 | 12.05 | 1.23 |
Results are presented as mean ± SD. We used one-way ANOVA for comparisons between different cell lines under different conditions.* P <0.05 compared with A549/DDP alone.
