Figure 2.

ILT2 is overexpressed on T cells from CLL patients. (A) PBMCs were obtained from 52 CLL patients and 20 healthy donors and the expression of ILT2 on T cells, and CD8 and CD4 T cell subsets was determined by staining the cells with CD3-, CD4-, CD8-, and ILT2-conjugated antibodies. Dot plots show the cytometric prolife of a CLL patient. Histograms in the right show flow cytometry profiles of a healthy donor and a representative patient. The comparison of the MFI of ILT2 surface expression on T cells (B), CD8 T cells (C) and CD4 T cells (D) between controls and patients is shown.