Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Naïve (T)cells require 2 signals to become activated: TCR/MHC and co-stimulation. The specific signal alone or the co-stimulatory signal alone leads to T cell anergy. The co-stimulatory signal is necessary for the synthesis and secretion of IL-2, which stimulates the T cell to divide and generate a larger population of memory and effector cells.
