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. 2017 Sep 13;65(11):627–636. doi: 10.1369/0022155417730021

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — (A) Results of G6PD gene sequencing, chromate inhibition, cytofluorometry, and spectrophotometric determination of G6PD activity and the G6PD:GR activity ratio to detect heterozygous G6PD deficiency. The Venn diagram indicates the number of females with a positive result in the tests, which implies G6PD deficiency. For example, 14 females had a positive result in all tests whereas 31 patients had a positive result of the G6PD:GR ratio determination only. (B) Results of G6PD gene sequencing, chromate inhibition, cytofluorometry, and spectrophotometric determination of G6PD activity and the G6PD:GR ratio to detect heterozygous G6PD deficiency. The Venn diagram indicates the number of females with a negative result in the tests, which implies normal G6PD function. For example, 9 females had a negative result in all tests whereas 9 patients only had a negative result in the G6PD activity determination. Abbreviations: G6PD, glucose-6-phosphate dehydrogenase; GR, glutathione reductase.