Table 4.
Characteristic | Sarcomere gene mutation (N=39) | Non-sarcomere gene mutation (N=47) | P Value |
---|---|---|---|
Age – yr | 26±14 | 26±18 | 0.90 |
Male sex — no. (%) | 31 (79) | 33 (70) | 0.33 |
| |||
LV volume parameters | |||
| |||
LVEF <50% – no. (%) | 15 (38) | 11 (23) | 0.13 |
LVEF – % | 46±18 | 52±13 | 0.07 |
LVEDVI – ml/m2 | 120±54 | 107±38 | 0.21 |
LVESVI – ml/m2 | 72±56 | 54±37 | 0.09 |
| |||
Distribution of non-compaction | |||
| |||
Number of affected segments | 8.8±3.1 | 7.6±2.9 | 0.07 |
Inter-ventricular septum affected – no. (%) | 14 (36) | 6 (13) | 0.01 |
Basal segments affected – no. (%) | 14 (36) | 10 (21) | 0.13 |
NC/C ratio | 2.7±0.9 | 2.5±0.8 | 0.30 |
Fulfilled CMR criteria for LVNC – no. (%) | 27 (69) | 27 (57) | 0.26 |
Phenotype: LVNC+ DCM+ | 11 (28) | 8 (17) | 0.21 |
Phenotype: LVNC+ DCM- | 16 (41) | 19 (40) | 0.96 |
Presence of LGE – no. (%) | 12 (31) | 3 (6) | 0.004 |
Multiple family members and subjects with simultaneous presence of mutations in both non-sarcomere and sarcomere genes were excluded. Abbreviations as in Table 1