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Iron homeostasis affects Ire1–mCherry clustering. (A) GO term enrichment of the hits in the screen based on the GOrilla analysis website. The table shows the ten highest enriched categories excluding redundant GO terms. In bold are all iron- and heme-related processes. (B) Deletion of several iron homeostasis genes disrupts Ire1–mCherry clustering following ER stress (2 mM DTT) (images from original screen). WT, wild type. Scale bar: 5 μm.
