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Subcellular distribution of PI(4,5)P2 within cilia of Lowe syndrome fibroblasts. Lowe syndrome fibroblasts exhibited increased PI(4,5)P2 in the transition zone of cilia. (A) Fibroblasts were immunostained with antibodies against Arl13b, γ-tubulin and PI(4,5)P2 or TCTN1. (B) Fibroblasts were immunostained with antibodies against acetylated α-tubulin and PI(4,5)P2 or MKS5. Scale bars: 2 µm.
