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. 2017 Oct 1;10(10):1201–1209. doi: 10.1242/dmm.030122

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Depletion of BAP complex subunits enhances Yki-induced hyperplasia. Confocal micrographs of wing imaginal discs expressing combinations of UAS-transgenes under apGal4 control. Discs were labeled with UAS-GFP to mark the transgene-expressing tissue (green) and with DAPI to label nuclei (red). (A) Control wing imaginal disc expressing GFP. (B) Wing imaginal disc expressing Yki. (C-G) Wing imaginal discs co-expressing UAS-Yki with UAS-RNAi transgenes to deplete expression of BAP complex subunit genes. Scale bars: 100 μm. (H) Quantification of tissue size (ap>Yki versus ap>Yki+BAP^RNAis, unpaired t-test, P<0.0001 for all).