Fig. 1.

MA plots at all four time points, highlighting a subset of developmentally regulated and breed-affected genes. These include muscle structural isoforms, mitochondrial metabolism and the causal mutation MSTN. The slow myosin isoforms being downregulated in the BA is consistent with a shift to a faster muscle phenotype in the mutant BA by 260 days. The strong developmental regulation in both breeds of C13H20ORF194 and MYH1 is also apparent. MSTN is consistently upregulated in the more muscular BA. We only included data from those genes >0.5 log DE in an effort to simplify the plots. The 0.5 threshold is an entirely arbitrary decision and is not meant to represent significance.