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. 2017 Oct 1;144(19):3533–3546. doi: 10.1242/dev.155598

Fig. 1.

Fig. 1.

Igf2 null mutants exhibit abnormalities in postnatal metatarsal bone growth. (A) Parameters used in metatarsal bone measurement. The darker area in the diaphysis indicates mineralized bone and calcified cartilage. Note that the same image is used in Fig. 5A. (B) Comparison of bone length between WT and Igf2 null bones at E15.5 and E17.5. (C) Comparison of bone width between WT and Igf2 null bones at E15.5 and E17.5. (D-G) Comparison of total bone length (D), bone width at diaphysis (E), length of the cartilage portion at metaphysis (F) and width of the cartilage portion at metaphysis (G) in WT and Igf2 null bones at postnatal stages P0-P21. At least eight embryonic bones/group and six postnatal bones/group were analyzed. Mean±s.d. *P<0.05 (unpaired t-tests between WT and Igf2 null).