Table 2. Summary of Mechanical Properties.
| DNA construct |
rheological properties |
|||
|---|---|---|---|---|
| cross-linker sequence | contour length (nm) | G0 (Pa) | σc (Pa) | σmax (Pa) |
| Noncovalent Cross-Linker | ||||
| ds-DNA C | 14 | 45 ± 1.5 | 3.5 ± 0.25 | 40 |
| ss-DNA LC (pH 7.4) | 26 | 34.5 ± 3.7 | 0.65 ± 0.05 | 18 ± 1.15 |
| ds-DNA LC | 19 | 40 ± 2.8 | 2.5 ± 0.25 | 22 |
| Covalent Cross-Linker | ||||
| ss-DNA AB | 16 | 8 | 2.3 | >200 |
| ds-DNA AB/C | 14 | 8.5 | 2.4 | >200 |
| pH Responsive i-Motif | ||||
| ss-DNA LC (pH 5.2) | 16 | 100 ± 6 | 4 ± 0.5 | 30 |
| pH Responsive Triple Helix | ||||
| DNA THC (pH 7.4) | 29 | 7.5 ± 0.5 | 0.65 ± 0.05 | 5.5 ± 0.75 |
| DNA THC (pH 5.2) | 5 | 16 ± 2.7 | 2 ± 0.25 | 5.5 ± 0.75 |
| Thrombin Responsive Aptamer | ||||
| DNA TB (without thrombin) | 23 | 11 | 0.6 | 3 |
| DNA TB (with thrombin) | 16 | 19 | 1.2 | 3 |