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. Author manuscript; available in PMC: 2017 Nov 22.
Published in final edited form as: Nat Genet. 2017 May 22;49(7):1107–1112. doi: 10.1038/ng.3869

Fig. 2. Results of SNP-based meta-analysis for intelligence based on 78,308 individuals.

Fig. 2

Association results from the GWAS meta-analysis pertaining to individuals of European descent. (a) Negative log10-transformed P-values for each SNP (y-axis) are plotted by chromosomal position (x-axis). The red and blue lines represent the thresholds for genome-wide statistical significant associations (P=5×10−8) and suggestive associations (P=1×10−5) respectively. Green dots represent the independent hits. (b) Functional categories for 336 genome-wide significant SNPs. (c) The minimum (most active) chromatine state across 127 tissues for 336 genome-wide significant SNPs. (d) The Regulome database score for 336 genome-wide significant SNPs. The lower the score the more likely it is that a SNP has a regulatory function. For b–d the numbers in brackets in the legends refer to the number of lead SNPs for that category.