Table 3.
Dose Cohort N |
80 n=4 |
100 n=7 |
120 n=3 |
140 n=8 |
160 n=12 |
Total n=34 |
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AE | Grade | 1/2 | 3/4 | 1/2 | 3/4 | 1/2 | 3/4 | 1/2 | 3/4 | 1/2 | 3/4 | 1/2 | 3/4 |
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Anemia | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 1 | 5 | |
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Leukopenia | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 4 | 1 | |
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Thrombocytopenia | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 2 | 2 | 5 |