Table 1. Data from tubule formation assay showing a change in various parameters of angiogenesis.
S.No. | Angiogenesis analyzer parameter | FRG1 overexpression vector | Control vector | P-value |
---|---|---|---|---|
1 | Number of extremities | 132 ± 25 | 107 ± 14 | 0.026 |
2 | Number of nodes | 263 ± 98 | 371 ± 96 | 0.039 |
3 | Number of junctions | 79 ± 28 | 110 ± 28 | 0.041 |
4 | Number of master junctions | 32 ± 16 | 46 ± 15 | 0.073 |
5 | Number of master segments | 51 ± 29 | 80 ± 28 | 0.057 |
6 | Total master segment length | 6288 ± 2837 | 9571 ± 2576 | 0.028 |
7 | Number of meshes | 16 ± 12 | 27 ± 12 | 0.057 |
8 | Total mesh area | 127029 ± 120136 | 306016 ± 163722 | 0.022 |
9 | Number of pieces | 183 ± 33 | 218 ± 36 | 0.052 |
10 | Number of segments | 83 ± 41 | 130 ± 43 | 0.039 |
11 | Number of branches | 69 ± 7 | 70 ± 8 | 0.41 |
12 | Number of isolated segments | 30 ± 11 | 17 ± 8 | 0.025 |
13 | Total length | 13624 ± 1677 | 15602 ± 1613 | 0.029 |
14 | Total branching length | 11200 ± 2393 | 14257 ± 2200 | 0.029 |
15 | Total segment length | 5964 ± 2756 | 9165 ± 2562 | 0.029 |
16 | Total branch length | 5236 ± 683 | 5091 ± 777 | 0.36 |
17 | Total isolated branches length | 2424 ± 867 | 1345 ± 620 | 0.014 |
18 | Branching interval | 87 ± 43 | 132 ± 41 | 0.046 |
19 | Mesh index | 200 ± 26 | 212 ± 28 | 0.22 |
20 | Mean mesh size | 6830 ± 1740 | 10358 ± 3523 | 0.024 |