Fig. 6.

Fenofibrate and ASO-Fsp27 reduce hepatic inflammation. A: Relative expression of selected proinflammatory transcripts. B: Representative micrographs of F4/80 immunohistochemical staining of paraffin-embedded liver sections. Dark brown precipitate indicates F4/80-positive macrophages. Scale bars represent 100 μm. RNA data are shown as means ± SEM (n = 5). *P ≤ 0.05, **P ≤ 0.01, compared with (ASO-ctrl, saline); ^‡‡P ≤ 0.01, significant interaction between ASO-Fsp27 and fenofibrate treatments.