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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Ann Biomed Eng. 2017 Jul 25;45(11):2626–2634. doi: 10.1007/s10439-017-1891-8

Figure 4.

Figure 4

Contrast-enhanced microCT can monitor the progressive degenerative changes in stab-, trypsin-, and collagenase- degeneration models. These changes can be monitored longitudinally, and enables the ability to quantify localized and nuanced changes within the IVD. The control samples showed clear presentation of the NP, while the stab- and trypsin- degeneration groups revealed a progressive loss of the NP attenuation. The collagenase samples show an immediate loss of the NP and collapse of the AF.