Table 2. Determinants of Patient Clinical Event-Risk.

	HR	95% CI	p - value
Patient Age	1.00	0.98 – 1.03	0.96
Caregiver Age	1.00	0.98 – 1.03	0.79
Patient NYHA Class III/IV	2.14	1.28 – 3.59	<0.01
Patient Cognition (MMSE)	0.98	0.94 – 1.02	0.30
Patient Comorbidities (Charlson)	1.06	0.90 – 1.25	0.49
Non-Spousal Caregiver	0.73	0.33 – 1.63	0.44
Caregiver Strain	0.94	0.91 – 0.97	<0.001
Caregiver Mental Health Status	0.97	0.94 – 0.99	0.02
Caregiver Contribution to Self-Care Maintenance	0.99	0.97 – 0.99	0.04
Caregiver Contributions to Self-Care Management	1.01	1.00 – 1.03	0.04

HR: hazards ratio; CI: confidence interval; NYHA: New York Heart Association; MMSE: Mini-Mental State Exam