Oxygenated MACF improves cell migration under hypoxia. Fibroblasts (A) and keratinocytes (B) where gown to confluency then scratched in vitro, imaged, then cultured with treatments under either normoxia (21% O2) or hypoxia (1% O2). At 24 h cultures were once again imaged. Quantification is shown on the left, white bars represent normoxia and black bars hypoxia results. All data n = 3–4, mean ± SD Letters are significantly different from one another by one-factor ANOVA (p < 0.0001). Representative images are presented on the right, with scale bars = 200 μm.