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. 2017 Oct 1;7(10):2032–2040.

Figure 4.

Figure 4

The proportion of each T cell subpopulation in the CMT-93 cells was determined by flow cytometry. FTD/TPI was administered orally from days 1 to 14 at the reported effective dose (150 mg/kg/day). Anti-mouse PD-1 mAb was injected intraperitoneally at a dose of 0.1 mg on days 1, 5, and 9. Combination therapy with FTD (150 mg/kg/day) and anti-mouse PD-1 mAb (0.1 mg/body) was administered on the same schedule as that of each monotherapy. CMT-93 tumors were collected 24 h after the final administration of the drugs (day 15). Values indicate means ± SD (n = 6). **P<0.01 by the Student’s one-sided t-test compared to the untreated control group.