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LP17 attenuates systematic inflammatory response. The concentration of TNF-α (A), IL-6 (B), and IL-1β (C) in serum was determined by ELISA assay in triplicate 12, 24, and 48 h after the first administration of saline, scrambled, or LP17. There were 8 rats in each group. NC, normal rats receiving saline; CLP-Scrambled peptides, rats with sepsis receiving scrambled peptide; CLP-LP17, rats with sepsis receiving LP17.
