Table 2.
Whole brain Voxel wise ReHo analysis results.
Region | L/R | Cluster | P value* | MNI (x,y.z) | |||
---|---|---|---|---|---|---|---|
Group Differences | |||||||
Aβ+> Aβ− | |||||||
Fusiform gyrus | L | 180 | <0.001 | −36 | −18 | −30 | |
Aβ+< Aβ− | |||||||
Precuneus | L | 118 | <0.001 | −9 | −57 | 27 | |
Mean FBB SUVR-ReHo correlations in Aβ + group | |||||||
Negative correlation | |||||||
Superior medial frontal gyrus | L | 401 | <0.001 | −9 | 51 | 21 | |
Superior medial frontal gyrus | R | 132 | <0.001 | 10 | 53 | 27 | |
Medial orbitofrontal gyrus | R | 121 | <0.001 | 2 | 45 | −22 | |
Precuneus | L | 189 | <0.001 | −9 | −57 | 30 | |
Precuneus | R | 107 | <0.001 | 5 | −59 | 26 | |
Angular gyrus | L | 89 | <0.001 | −40 | −63 | 27 | |
Positive correlation | |||||||
Lingual gyrus | R | 296 | <0.001 | 9 | −75 | 3 | |
Lingual gyrus | L | 271 | <0.001 | −8 | −75 | −1 | |
Fusiform gyrus | L | 112 | <0.001 | −36 | −37 | −28 | |
Middle temporal gyrus | R | 82 | <0.001 | 46 | −25 | −10 |
*Alphasim corrected P < 0.001 values for the multiple comparisons. ReHo = regional homogeneity, Aβ+ = cognitively normal older adults with beta amyloid retention, Aβ− = cognitively normal older adults without beta amyloid retention, FBB = 18F-Florbetaben, SUVR = standardized uptake value ratio, MNI = Montreal Neurological Institute coordinate.