Table 3.
Top 10 significantly up- and downregulated genes, ExpPE vs. Pr.
| Gene name | Fold change | p-value |
|---|---|---|
| Ttn | 8.16 | 0.049 |
| Tnni1 | 3.27 | 0.039 |
| RGD1564480 | 2.49 | 0.004 |
| Syngr3 | 2.48 | 0.031 |
| Ugt1a1 | 2.46 | 0.021 |
| Rab6b | 2.34 | 0.041 |
| Scg3 | 2.30 | 0.025 |
| Snca | 2.29 | 0.007 |
| Mcpt9 | 2.26 | 0.008 |
| Add2 | 2.26 | 0.028 |
| Nlrp1b | −2.97 | 0.023 |
| Ccl11 | −2.57 | 0.007 |
| LOC100359993 | −2.55 | 0.017 |
| RGD1561778 | −2.51 | 0.002 |
| LOC100361319 | −2.15 | 0.008 |
| LOC681325 | −2.12 | 0.005 |
| RT1-CE5 | −2.12 | 0.026 |
| Rpl23a | −2.10 | 0.022 |
| Cd180 | −2.06 | 0.002 |
| Wnt16 | −2.05 | 0.014 |
Gene expression was measured with a whole-genome microarray. ExpPE = Experimental Preeclampsia; Pr = healthy Pregnant.