Skip to main content
. 2017 Nov 1;7:14824. doi: 10.1038/s41598-017-14809-8

Figure 2.

Figure 2

BMP4 induces expression of uroplakin in the developing collecting ducts. Developing collecting ducts were treated globally with BMP4 and uroplakin expression was investigated after 5 days of culture. (A) E11.5 kidney rudiments were cultured in media containing vehicle only (BSA), 25 ng/ml of BMP4 or 100ng/ml of BMP4. (B) Globally BMP4-treated E11.5 kidney rudiments were cultured in the presence of a Gremlin soaked bead or vehicle only soaked bead. *Bead location, n = a few examples of developing nephrons. Scale (unless otherwise stated) = 100 µM.