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Effects of thalidomide on inflammatory mediators in BALF. Cytokines including IL-6, IL-8, TNF-α, and TGF-β in lung homogenates and serum were determined using ELISA. All these cytokines were significantly increased by bleomycin treatment. However, thalidomide reduced the values of these cytokines significantly in a dose dependent manner. All the data were shown as mean ± SD of eight rats. #P < 0.05 vs. control group, *P < 0.05 vs. bleomycin treated group.
