Table 1.
Effect of thalidomide on bleomycin induced changes in total and differential cell counts in the BALF of rats
| Group | Total cells (×105/ml) | Neutrophils (×104/ml) | Macrophages (×105/ml) | Lymphocytes (×104/ml) |
|---|---|---|---|---|
| Control | 2.21 ± 0.55 | 4.93 ± 0.47 | 1.40 ± 0.53 | 3.24 ± 0.64 |
| Bleomycin | 12.30 ± 1.38# | 22.11 ± 2.15# | 7.92 ± 1.88# | 21.69 ± 2.43# |
| Thalidomide (10 mg/kg) | 9.23 ± 1.24* | 14.24 ± 2.81* | 6.93 ± 1.92 | 17.76 ± 2.13 |
| Thalidomide (20 mg/kg) | 7.82 ± 0.94* | 8.93 ± 1.11* | 5.91 ± 1.69* | 10.17 ± 2.36* |
| Thalidomide (50 mg/kg) | 5.45 ± 0.87* | 6.16 ± 1.18* | 3.97 ± 0.95* | 8.64 ± 2.38* |
Values are mean ± SD.
#
P < 0.05 vs. Control group;
*
P < 0.05 vs. bleomycin treated group.