Figure 1.

Overexpression of NOX4 in GC. A. The mRNA level of NOX4 in GC (n=120) and normal tissues (n=43) was detected by real-time PCR. NOX4 mRNA was significantly elevated in GC tissues as compared with non-tumorous tissues (P<0.0001). B. NOX4 expression was significantly increased in GC tissues (n=250) when compared with normal tissues (n=32) from TCGA STAD dataset (P<0.0001). C. Overall survival analysis showed that patients with NOX4 higher expression tumors have a shorter overall survival time than those with NOX4 lower expression tumors (P<0.05). (*P<0.05, **P<0.01, ***P<0.001).