Figure 2.

Variation in eGFR, folic acid, and vitamin B₁₂ levels with tHCY level in controls and subgroups of IS patients with different renal function. A. tHCY level was lower in normal tHCY patients (NHCY) or controls than in hyperhomocysteinemic patients (HHCY) or controls. B-D. eGFR and levels of folic acid and vitamin B₁₂ were lower in HHCY subgroups than in NHCY subgroups of controls or IS patients with normal renal function. By contrast, eGFR and levels of folic acid and vitamin B₁₂ were similar between NHCY and HHCY subgroups in IS patients with RI. Median N, median for NHCY subgroups; median H, median for HHCY subgroups. Compared with NHCY group, #P<0.05, *P<0.01.