Figure 1.

SDCBP knockdown suppressed glioma cell proliferation and invasion. A. SDCBP mRNA (top) and protein expression (bottom) in glioma cell lines. B. T98G and U87 cells were transfected with SDCBP siRNA (siSDCBP) or control siRNA (siNC). At 48 h after transfection, knockdown efficiency was evaluated using qPCR (top) and western blot (bottom). C. Cell proliferation rates were assessed by CCK-8 assay. D. Cell invasion was evaluated in Matrigel-coated Transwell chambers. Representative images are shown at the original magnification: 200 × (left panel). Invasion was quantified using five fields per triplicate well (right panel). ***P<0.001 vs. siNC.