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. 2017 Oct 25;7(10):170133. doi: 10.1098/rsob.170133

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© 2017 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 8. — Cell signalling induced by wt and mutant-CXCL13. (a) Dose-dependent CXCL13-induced chemotaxis of wt- (black squares), C1.5- (blue triangles) and ΔN- (red triangles) CXCL13. (b) Intracellular calcium mobilization induced by wt- (black squares) and C1.5- (blue triangles) CXCL13 on CXCR5-transfected CHO 677 cells. (c) Dose-dependent CXCL13-induced chemotaxis of CXCL13 (black triangles) or CXCL13–dp4 (blue triangles). The percentages of migrated splenocytes over the total number of cells or the level of calcium intakes (arbitrary unit) are presented as the mean ± s.d. of three independent experiments.