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. 2017 Oct 26;12:7885–7896. doi: 10.2147/IJN.S141882

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© 2017 Ren et al. This work is published and licensed by Dove Medical Press Limited

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Antitumor activity in vivo. (A) Relative tumor volume in mice from different treatment groups. (B) hTERT mRNA and protein expression in MCF-7 tumor-bearing mice in vivo. *P<0.01, PEI-SWNT/pHSP-shT versus the other three groups. (C) H&E-stained tumor tissues in mice. The scale bar is 50 μm.

Abbreviations: HSP, heat-shock protein; hTERT, human telomerase reverse transcriptase; PEI-SWNT, polyetherimide-modified single-wall carbon nanotube; shT, short hairpin RNA of human telomerase reverse transcriptase.