Table 3. Characteristics of the four patients with HBsAg seroclearance.
| Patient | Sex/age | ALT (U/l) |
HBeAg |
HBsAg (log IU/ml) |
HBcrAg (log kU/ml) |
HBV DNA (log IU/ml) |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Baseline | Time of HBeAg seroconversion | Baseline | Annual decline | Time of HBsAg seroclearance | Baseline | Time of undetectable HBcrAg | Baseline | Time of undetectable HBV DNA | ||
| 1 | M/46 | 44 | Neg | — | 1.83 | 1.57 | 2nd year | 0.30 | NA | 4.59 | 1st year |
| 2 | M/29 | 622 | Pos | 3rd year | 5.64 | 0.99 | 7th year | 5.93 | 7th year | 8.11 | 1st year |
| 3 | M/51 | 37 | Neg | — | 2.11 | 0.57 | 6th year | 0.51 | 5th year | 4.12 | 1st year |
| 4 | M/45 | 128 | Neg | — | 2.76 | 0.58 | 7th year | NA | NA | 4.90 | 1st year |
Abbreviations: ALT, alanine aminotransferase; HBcrAg, hepatitis B core-related antigen; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV DNA, hepatitis B virus DNA; NA, not available; Neg, negative; Pos, positive; UD, undetectable.