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. 2017 Oct 20;44(10):493–501. doi: 10.1016/j.jgg.2017.06.003

Fig. 5.

Fig. 5

Overexpression of TBPH does not modify neurodegeneration associated with knockdown of Npl4 or Ufd1. A: PCR validation of TBPH overexpression (OE) in UAS-TBPH::Venus larvae compared to control larvae. B and C: Neuronal-specific OE of TBPH did not significantly modify locomotor deficits caused by knockdown of Npl4 or Ufd1 (generated using nSyb-GAL4) in either larvae (B, P values determined by one-way ANOVA and Tukey's post-tests; n = 3–10 experiments, 10 larvae from per experiment; ns P > 0.05, **P < 0.01, ****P < 0.0001) or adult flies (C, n = 8–18 experiments, 10 flies per experiment). D: Neuronal OE of TBPH did not significantly modify the lifespan of these flies (P > 0.05 by log-rank tests; n = 84–180 flies).