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Proposed model for sulfide oxidation by FCSD and PDO in C. necator H16. Sulfide is oxidized by FCSD to polysulfide in the periplasmic space (PS). Polysulfide moves into the cytoplasm in an unknown way, and it is oxidized by PDO to produce sulfite in the cytoplasm. Sulfite is transported into the periplasmic space by a transport protein. Polysulfide and sulfite react to produce thiosulfate in both the periplasmic space and the cytoplasm. OM, outer membrane; IM, inner membrane.
