. 2017 Oct 31;8(5):e00517-17. doi: 10.1128/mBio.00517-17

TABLE 2 .

Aztreonam MICs and mutated resistance genes in clinical P. aeruginosa strains

Patient identifier	Aztreonam MIC (μg/ml) for isolate		Mutation(s) in gene^a:
Patient identifier	Susceptible isolate	Increased- resistance isolate	mexR	ftsI	clpA	ampC	phoQ	mpl	nalC	nalD	dacB	PA3206	pgi	atpD	pepA
3	6	256		G531D, A513T		Q155R, V239A, V356I	G301G	M38fs				R274H
6	5	58	S88fs	G191D
12	0.5	256		S543G, A60V			H223Y						G469S		G214S
13	0.19	256		R504C, G63D										H169R	W414*
15	16	256
17	12	32		A244T
18	5	24	V16fs
22	24	256	V5fs	I524S		N347T		P62fs							R26fs
28	8	256		R504H, A482V, N242S		G183S, V239A, V356I		M38fs		L22P		G208D
31	2	256		Y367C		R126C, G183S
34	0.19	8
44	8	256		I524T, T267A	G105E	V239A, D245G			E10E		Y264C
46	8	256										C272R
90	0.38	256		A244T	G105R
Vx611	0.125	256		P527S	E635G			M38fs

^{^a}

Fractions of strains with nonsynonymous mutations in each gene were as follows: mexR, 0.20; ftsI, 0.73; clpA, 0.20; ampC, 0.33; phoQ, 0.13; mpl, 0.27; nalC, 0.07; nalD, 0.07; dacB, 0.07; PA3206, 0.20; pgi, 0.07; atpD, 0.07; pepA, 0.20.