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. 2017 Jun 27;30(11):1529–1539. doi: 10.5713/ajas.17.0154

Table 5.

Known meat production related genes included in the list of genes with differentially methylated regions (DMRs) in their flanking region and gene bodies

Differentially methylated regions (DMR) Previous published studies for DMR related genes


Chromosome Start End Type Gene elements Gene Animal Phenotype Reference
14 47508715 47510424 hypomethylation Exon RYR1 Pig Daily weight gain Kadarmideen [14]
19 56580593 56581899 hypomethylation Exon PPARG2 Cattle Carcass traits Fan et al [15]
7 84215883 84217928 hypermethylation Promoter TGFB3 Chicken Growth traits Jin et al [16]
5 1961358 1961794 hypermethylation Intron ADAMTS2 Sheep Post-weaning gain Zhang et al [4]
5 1961358 1961794 hypermethylation Intron ADAMTS2 Cattle fat content of muscle Lee et al [17]
11 28039026 28040412 hypomethylation Intron NTN1 Sheep Post-weaning gain Zhang et al [4]
16 4132670 4134204 hypomethylation Exon SH3PXD2B Mice Postnatal growth Mao et al [18]
16 4134519 4135224 hypomethylation Intron SH3PXD2B Mice Postnatal growth Mao et al [18]
26 13938540 13939276 hypermethylation Exon ACSL1 Cattle Fatty acids of skeletal muscle Widmann et al [19]

RYR1, ryanodine receptor 1; PPARG2, peroxisome proliferator activated receptor-gamma 2; TGFB3, transforming growth factor beta 3; ADAMTS2, ADAM metallopeptidase with thrombospondin type 1 motif 2; NTN1, netrin 1; SH3PXD2B, SH3 and PX domains 2B; ACSL1, acyl-CoA synthetase long chain family member 1.