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. 2017 Sep 21;7(11):1686–1695. doi: 10.1002/2211-5463.12301

Figure 5.

Figure 5

Sodium hydrosulfide attenuated the PC12 cellular injury induced by OGD/R by suppressing autophagy. (A) A western blot detecting p62 in PC12 cells. (B) Rapamycin, a stimulator of autophagy, decreased the expression of p62, but 3‐MA, an inhibitor of autophagy, increased the expression of p62 (n = 4). (C) Rapamycin increased the caspase‐3 luminescence compared with NaHS treatment, but 3‐MA decreased the caspase‐3 luminescence compared with OGD/R treatment (n = 4). (D) Rapamycin increased the LDH activity in the supernatant compared with NaHS treatment, but 3‐MA decreased the LDH activity in the supernatant compared with OGD/R treatment (n = 4). *P < 0.05 compared with the normal group; #P < 0.05 compared with the OGD/R group; &P < 0.05 compared with the OGD/R + NaHS group.