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. 2017 Oct 13;15(10):303. doi: 10.3390/md15100303

Figure 4.

Figure 4

Schematic figurative representation of a NaV channel indicating the four α-subunit domains (I–IV). Each domain has six transmembrane segments S1–S6 (shown as protein spirals). The pore-forming segments (S5–S6) in each domain are indicated in blue.