Table 1.
Relative acute toxicities of STX (=1.0) and some derivatives according to intraperitoneal mouse bioassay (IP MBA) data compiled by Durán-Riveroll et al. [39] with values calculated from * Sullivan et al. [40] and ** Oshima [41]. Relative oral toxicity values in mice by voluntary feeding/gavage are according to Munday et al. [42].
| Toxin Analog | Relative Toxicity IP MBA | Relative Toxicity Voluntary Feeding/Gavage |
|---|---|---|
| STX | 1.0 | 1.0 |
| NEO | 1.0 | 2.5/1.7 |
| GTX1 | 1.0 | |
| GTX4 | 0.7 | |
| GTX1/4 | 0.9/0.7 | |
| GTX2 | 0.4 | |
| GTX3 | 0.6 | |
| GTX2/3 | 0.6/0.5 | |
| dcSTX | 1.0 | |
| dcGTX1 | 0.5 * | |
| dcGTX4 | 0.5 * | |
| dcGTX2 | 0.2 | |
| dcGTX3 | 0.4 | |
| dcGTX2/3 | 0.1/0.2 | |
| dcNEO | 0.4 | 0.2/0.2 |
| B1 | 0.1 | 0.06/0.05 |
| B2 | 0.1 | <0.02/0.04 |
| C1 | 0.01 ** | |
| C2 | 0.1 | |
| C1/2 | 0.04/0.03 | |
| C3 | 0.01 ** | |
| C4 | 0.1 |