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. 2017 Oct 13;15(10):311. doi: 10.3390/md15100311

Table 1.

Angiotensin I-converting enzyme (ACE) inhibitory activity, recovery yield, protein and peptide contents of F. spiralis protein hydrolysate (FSPH) fractions obtained by ultrafiltration.

Sample Yield (mg/g of DW FSPH) ACE-Inhibition Protein Content (mg/g of DW FSPH) Peptide Content (mg/g of DW FSPH)
Percentage IC50 Value (mg/mL)
Fr1 < 1 kDa 206.28 45.08 ± 0.66 a 1.850 ± 0.06 b 123.15 ± 2.78 a 43.81 ± 2.27 a
1 kDa ≤ Fr2 < 3 kDa 53.72 41.93 ± 1.62 a 2.000 ± 0.06 b 336.28 ± 4.96 b 35.91 ± 1.58 a
Fr3 ≥ 3 kDa 703.95 86.85 ± 1.89 b 0.500 ± 0.03 a 474.03 ± 4.44 b 243.82 ± 2.9 b

Values are mean ± SD (n = 3). Different superscript letters are significantly different (p < 0.05). IC50 value defined as the concentration which inhibits 50% of the ACE activity (tested concentration = 2 mg/mL). Captopril, used as a positive control for ACE-inhibition, showed an IC50 value of 0.163 ng/mL. DW, dry weight.