Table 4.
Subgroup Analysis of Hypertension Patients: Univariate and Multivariate Analyses of Factors Associated with Increased Albuminuria.
| Men (n = 178) | Women (n = 265) | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariate Model | Multivariate Model | Univariate Model | Multivariate Model | |||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age | 0.954 | 0.800 | ||||||
| 50-59 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 60-69 | 1.061 [0.406,2.772] | 0.903 | 1.25 [0.451,3.459] | 0.667 | ||||
| 70-79 | 0.946 [0.332,2.698] | 0.917 | 1.602 [0.594,4.32] | 0.351 | ||||
| 80- | 0.578 [0.063,5.296] | 0.627 | 1.301 [0.331,5.121] | 0.706 | ||||
| BMI | 0.112 | |||||||
| < 18.5 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 18.5≤ <23.0 | NA* | NA* | 0.143 [0.025,0.807] | 0.027 | ||||
| 23.0≤ <25 | NA* | NA* | 0.265 [0.048,1.471] | 0.129 | ||||
| ≥ 25 | NA* | NA* | 0.175 [0.033,0.935] | 0.041 | ||||
| Current Smoking | 0.359 | 0.852 | ||||||
| (Current vs. Never) | 4.765 [0.559,40.64] | 0.153 | 0.777 [0.169,3.577] | 0.746 | ||||
| (Past vs. Never) | 4.125 [0.522,32.568] | 0.178 | 1.444 [0.289,7.204] | 0.654 | ||||
| Alcohol intake >3 Unit/d | 1.667 [0.672 , 4.133] | 0.270 | NA# | NA# | ||||
| Physical activity | 0.566 [0.203,1.575] | 0.275 | 1.167 [0.501,2.716] | 0.720 | ||||
| Diabetes | 3.529 [1.584,7.865] | 0.002 | 3.531 [1.421,8.774] | 0.006 | 1.197 [0.564,2.54] | 0.639 | ||
| Dyslipidaemia | 2.126 [0.854,5.29] | 0.104 | 1.537 [0.779,3.033] | 0.215 | ||||
| History of CVD | 1.957 [0.81,4.727] | 0.135 | 0.919 [0.36,2.344] | 0.859 | ||||
| Metabolic syndrome | 2.883 [1.175,7.075] | 0.020 | 1.743 [0.605,5.025] | 0.303 | 0.631 [0.322,1.236] | 0.179 | ||
| Vitamin D deficiency (<20 ng/ml)) | 1.012 [0.947,1.082] | 0.722 | 1.017 [0.971,1.065] | 0.472 | ||||
| Estrogen replacement | _ | _ | _ | _ | 0.72 [0.265,1.958] | 0.520 | ||
| eGFR <60ml/min/1.73m2 | 0.969 [0.946,0.993] | 0.010 | 0.983 [0.964,1.002] | 0.080 | ||||
| Skeletal muscle mass | 0.0009 | 0.639 | ||||||
| Normal SMI | 1.00 (Reference) | 1.00 (Reference) | ||||||
| Mild LMM | 1.448 [0.605,3.466] | 0.405 | 1.182 [0.464,3.006] | 0.726 | 0.778 [0.378,1.6] | 0.494 | ||
| Severe LMM | 10.954 [3.108,38.61] | 0.0002 | 11.449 [3.037,43.156] | 0.0003 | 0.667 [0.253,1.754] | 0.411 | ||
* In men, the number of subjects with BMI < 18.5 (the reference group) was 16 (3.25%), which was a too small number that an odds ratio for the other groups cannot be calculated.
# In women, the number of subjects taking alcohol >3Unit/d was too small, that an odds ratio for the other groups cannot be calculated.