Table 5.
Subgroup Analysis of Non-diabetes Patients: Univariate and Multivariate Analyses of Factors Associated with Increased Albuminuria.
| Men (n = 417) | Women (n = 512) | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariate Model | Multivariate Model | Univariate Model | Multivariate Model | |||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age | 0.504 | 0.583 | ||||||
| 50-59 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 60-69 | 1.385 [0.6,3.198] | 0.445 | 1.403 [0.693,2.84] | 0.346 | ||||
| 70-79 | 1.786 [0.743,4.294] | 0.195 | 1.547 [0.735,3.258] | 0.250 | ||||
| 80- | 2.273 [0.579,8.917] | 0.239 | 1.851 [0.624,5.485] | 0.266 | ||||
| BMI | 0.283 | 0.525 | ||||||
| < 18.5 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 18.5≤ <23.0 | 1.469 [0.18,11.96] | 0.719 | 0.441 [0.114,1.703] | 0.235 | ||||
| 23.0≤ <25 | 0.921 [0.106,8.013] | 0.941 | 0.481 [0.121,1.914] | 0.299 | ||||
| ≥ 25 | 2.222 [0.275,17.988] | 0.454 | 0.635 [0.168,2.399] | 0.503 | ||||
| Current Smoking | 0.292 | 0.485 | ||||||
| (Current vs. Never) | 3.262 [0.724,14.696] | 0.124 | 0.342 [0.045,2.579] | 0.297 | ||||
| (Past vs. Never) | 2.548 [0.577,11.255] | 0.217 | 1.57 [0.335,7.358] | 0.567 | ||||
| Alcohol intake >3 Unit/d | 0.540 [0.185,1.572] | 0.258 | NA* | NA* | ||||
| Physical activity | 0.885 [0.391,2] | 0.768 | 0.904 [0.439,1.862] | 0.784 | ||||
| Hypertension | 1.754 [0.893,3.445] | 0.103 | 2.266 [1.288,3.987] | 0.005 | ||||
| Dyslipidaemia | 2.312 [1.116,4.791] | 0.024 | 1.462 [0.634,3.375] | 0.373 | 1.638 [0.923,2.905] | 0.091 | ||
| History of CVD | 2.188 [0.847,5.647] | 0.105 | 0.657 [0.196,2.208] | 0.497 | ||||
| Metabolic syndrome | 2.453 [1.248,4.823] | 0.009 | 1.257 [0.541,2.921] | 0.594 | 1.071 [0.611,1.877] | 0.811 | ||
| Vitamin D deficiency (<20 ng/ml)) | 1.049 [0.993,1.108] | 0.086 | 1.028 [0.984,1.074] | 0.218 | ||||
| Estrogen replacement | _ | _ | _ | _ | 0.547 [0.211,1.42] | 0.215 | ||
| eGFR <60ml/min/1.73m2 | 0.962 [0.94,0.984] | 0.0008 | 0.976 [0.952,1] | 0.055 | 0.998 [0.98,1.016] | 0.844 | ||
| Skeletal muscle mass | 0.0003 | 0.009 | ||||||
| Normal SMI | 1.00 (Reference) | 1.00 (Reference) | ||||||
| Mild LMM | 1.313 [0.583,2.958] | 0.511 | 1.174 [0.475,2.903] | 0.728 | 1.146 [0.622,2.113] | 0.662 | ||
| Severe LMM | 8.782 [3.046,25.322] | <.0001 | 6.185 [1.889,20.251] | 0.003 | 0.784 [0.292,2.102] | 0.629 | ||
* In women, the number of subjects taking alcohol >3Unit/d was too small, that an odds ratio for the other groups cannot be calculated.