Table 6.
Subgroup Analysis of Non-metabolic Syndrome Patients: Univariate and Multivariate Analyses of Factors Associated with Increased Albuminuria.
| Men (n = 317) | Women (n - 310) | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariate Model | Multivariate Model | Univariate Model | Multivariate Model | |||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age | 0.696 | 0.031 | 0.164 | |||||
| 50-59 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 60-69 | 1.234 [0.446,3.412] | 0.685 | 2.823 [1.019,7.816] | 0.045 | 2.014 [0.698,5.806] | 0.195 | ||
| 70-79 | 1.45 [0.504,4.172] | 0.490 | 4.704 [1.674,13.219] | 0.003 | 3.229 [1.042,10.003] | 0.042 | ||
| 80- | 2.29 [0.557,9.404] | 0.250 | 3.477 [0.909,13.298] | 0.068 | 3.833 [0.823,17.859] | 0.087 | ||
| BMI | 0.387 | 0.379 | ||||||
| < 18.5 | 1.00 (Reference) | 1.00 (Reference) | ||||||
| 18.5≤ <23.0 | 1.63 [0.202,13.18] | 0.646 | 0.42 [0.106,1.655] | 0.214 | ||||
| 23.0≤ <25 | 0.615 [0.064,5.912] | 0.674 | 0.378 [0.086,1.668] | 0.199 | ||||
| ≥ 25 | 1.167 [0.12,11.301] | 0.894 | 0.72 [0.169,3.071] | 0.657 | ||||
| Current Smoking | 0.531 | 0.814 | ||||||
| (Current vs. Never) | 2.2 [0.466,10.395] | 0.319 | 0.517 [0.066,4.043] | 0.529 | ||||
| (Past vs. Never) | 1.563 [0.338,7.221] | 0.567 | 0.861 [0.106,7.022] | 0.888 | ||||
| Alcohol intake >3 Unit/d | 0.864 [0.286,2.612] | 0.795 | NA* | NA* | ||||
| Physical activity | 0.824 [0.3,2.269] | 0.708 | 0.508 [0.172,1.5] | 0.220 | ||||
| Diabetes | 5.561 [1.946,15.89] | 0.001 | 4.495 [1.495,13.513] | 0.007 | 2.086 [0.424,10.252] | 0.365 | ||
| Hypertension | 1.243 [0.501,3.083] | 0.639 | 3.297 [1.592,6.829] | 0.001 | 3.354 [1.497,7.514] | 0.003 | ||
| Dyslipidaemia | 1.94 [0.851,4.422] | 0.115 | 1.777 [0.838,3.766] | 0.133 | ||||
| History of CVD | 2.182 [0.693,6.871] | 0.182 | 1.703 [0.467,6.214] | 0.420 | ||||
| Vitamin D deficiency (<20 ng/ml)) | 1.017 [0.95,1.089] | 0.629 | 1.069 [1.011,1.13] | 0.018 | 1.067 [1.007,1.13] | 0.027 | ||
| Estrogen replacement | _ | _ | _ | _ | 0.586 [0.171,2.009] | 0.394 | ||
| eGFR <60ml/min/1.73m2 | 0.988 [0.962,1.015] | 0.395 | 0.991 [0.967,1.015] | 0.438 | ||||
| Skeletal muscle mass | 0.007 | 0.030 | 0.546 | |||||
| Normal SMI | 1.00 (Reference) | 1.00 (Reference) | ||||||
| Mild LMM | 2.025 [0.792,5.174] | 0.140 | 1.923 [0.739,5.009] | 0.180 | 1.131 [0.499,2.561] | 0.767 | ||
| Severe LMM | 11.063 [2.278,53.722] | 0.002 | 8.183 [1.539,43.495] | 0.013 | 0.345 [0.045,2.665] | 0.307 | ||
* In women, the number of subjects taking alcohol >3Unit/d was too small, that an odds ratio for the other groups cannot be calculated.