Table 2.
Distribution frequencies of MTNR1A genotypes in 272 controls and 272 urothelial cell carcinoma patients
| Variable | Controls (N=272) n (%) | Patients (N=272) n (%) | OR (95% CI) |
|---|---|---|---|
| rs2119882 | |||
| TT | 113 (41.5%) | 108 (39.7%) | 1.00 |
| TC | 129 (47.4%) | 119 (43.8%) | 0.965 (0.672~1.387) |
| CC | 30 (11.1%) | 45 (16.5%) | 1.569 (0.922~2.672) |
| TC+CC | 159 (58.5%) | 164 (60.3%) | 1.079 (0.766~1.520) |
| rs2119882 Alleles | Controls (N=544) n (%) | Patients (N=544) n (%) | |
| T | 355 (65.3%) | 335 (61.6%) | 1.00 |
| C | 189 (34.7%) | 209 (38.4%) | 1.172 (0.915~1.500) |
| rs13140012 | |||
| AA | 111 (40.8%) | 103 (37.9%) | 1.00 |
| AT | 122 (44.9%) | 130 (47.8%) | 1.148 (0.797~1.654) |
| TT | 39 (14.3%) | 39 (14.3%) | 1.078 (0.642~1.810) |
| AT+TT | 161 (59.2%) | 169 (62.1%) | 1.131 (0.802~1.596) |
| rs13140012 Alleles | Controls (N=544) n (%) | Patients (N=544) n (%) | |
| A | 344 (63.2%) | 336 (61.8%) | 1.00 |
| T | 200 (36.8%) | 208 (38.2%) | 1.065 (0.833~1.361) |
| rs6553010 | |||
| AA | 124 (45.6%) | 114 (41.9%) | 1.00 |
| AG | 105 (38.6%) | 103 (37.9%) | 1.067 (0.735~1.548) |
| GG | 43 (15.8%) | 55 (20.2%) | 1.391 (0.867~2.233) |
| AG+GG | 148 (54.4%) | 158 (58.1%) | 1.161 (0.827~1.630) |
| rs6553010 Alleles | Controls (N=544) n (%) | Patients (N=544) n (%) | |
| A | 353 (64.9%) | 331 (60.8%) | 1.00 |
| G | 191 (35.1%) | 213 (39.2%) | 1.189 (0.930~1.521) |
The odds ratios (ORs) and with their 95% confidence intervals (CIs) were estimated by logistic regression models.