Table 3.
Distribution frequencies of the clinical status and MTNR1A rs2119882 genotype frequencies of 272 patients with urothelial cell carcinoma
| Variable | MTNR1A (rs2119882) | |||
|---|---|---|---|---|
| TT (%) (n=108) | TC+CC (%) (n=164) | OR (95% CI) | p value | |
| Stage | ||||
| Superficial tumor (pTa~pT1) | 72 (66.7%) | 93 (56.7%) | 1.00 | |
| Invasive tumor (pT2~pT4) | 36 (33.3%) | 71 (43.3%) | 1.527 (0.921~2.531) | p=0.100 |
| Tumor T status | ||||
| T0 | 33 (30.6%) | 41 (25.0%) | 1.00 | |
| T1~T4 | 75 (69.4%) | 123 (75.0%) | 1.320 (0.769~2.267) | p=0.314 |
| Lymph node status | ||||
| N0 | 99 (91.7%) | 145 (88.4%) | 1.00 | |
| N1+N2 | 9 (8.3%) | 19 (11.6%) | 1.441 (0.626~3.316) | p=0.388 |
| Metastasis | ||||
| M0 | 107 (99.1%) | 161 (98.2%) | 1.00 | |
| M1 | 1 (0.9%) | 3 (1.8%) | 1.994 (0.205~19.421) | p=0.545 |
| Histopathologic grading | ||||
| Low grade | 11 (10.2%) | 28 (17.1%) | 1.00 | |
| High grade | 97 (89.8%) | 136 (82.9%) | 0.551 (0.262~1.160) | p=0.113 |
OR, odds ratio; CI, confidence interval.