Table 4.
Distribution frequencies of the clinical status and MTNR1A rs13140012 genotype frequencies in 272 patients with urothelial cell carcinoma
| Variable | MTNR1A (rs13140012) | |||
|---|---|---|---|---|
| AA (%) (n=103) | AT+TT (%) (n=169) | OR (95% CI) | p value | |
| Stage | ||||
| Superficial tumor (pTa~pT1) | 69 (67.0%) | 96 (56.8%) | 1.00 | |
| Invasive tumor (pT2~pT4) | 34 (33.0%) | 73 (43.2%) | 1.543 (0.926~2.573) | p=0.095 |
| Tumor T status | ||||
| T0 | 29 (28.2%) | 45 (26.6%) | 1.00 | |
| T1~T4 | 74 (71.8%) | 124 (73.4%) | 1.080 (0.624~1.869) | p=0.784 |
| Lymph node status | ||||
| N0 | 94 (91.3%) | 150 (88.8%) | 1.00 | |
| N1+N2 | 9 (8.7%) | 19 (11.2%) | 1.323 (0.575~3.046) | p=0.510 |
| Metastasis | ||||
| M0 | 102 (99.0%) | 166 (98.2%) | 1.00 | |
| M1 | 1 (1.0%) | 3 (1.8%) | 1.843 (0.189~17.960) | p=0.593 |
| Histopathologic grading | ||||
| Low grade | 10 (9.7%) | 29 (17.2%) | 1.00 | |
| High grade | 93 (90.3%) | 140 (82.8%) | 0.519 (0.242~1.116) | p=0.089 |
OR, odds ratio; CI, confidence interval.