Table 5.
Distribution frequencies of the clinical status and MTNR1A rs6553010 genotype frequencies in 272 patients with urothelial cell carcinoma
| Variable | MTNR1A (rs6553010) | |||
|---|---|---|---|---|
| AA (%) (n=114) | AG+GG (%) (n=158) | OR (95% CI) | p value | |
| Stage | ||||
| Superficial tumor (pTa~pT1) | 78 (68.4%) | 87 (55.1%) | 1.00 | |
| Invasive tumor (pT2~pT4) | 36 (31.6%) | 71 (44.9%) | 1.768 (1.068~2.928) | p=0.026* |
| Tumor T status | ||||
| T0 | 32 (28.1%) | 42 (26.6%) | 1.00 | |
| T1~T4 | 82 (71.9%) | 116 (73.4%) | 1.078 (0.628~1.849) | p=0.786 |
| Lymph node status | ||||
| N0 | 101 (88.6%) | 143 (90.5%) | 1.00 | |
| N1+N2 | 13 (11.4%) | 15 (9.5%) | 0.815 (0.372-1.787) | p=0.609 |
| Metastasis | ||||
| M0 | 112 (98.2%) | 156 (98.7%) | 1.00 | |
| M1 | 2 (1.8%) | 2 (1.3%) | 0.718 (0.100-5.174) | p=0.741 |
| Histopathologic grading | ||||
| Low grade | 13 (11.4%) | 26 (16.5%) | 1.00 | |
| High grade | 101 (88.6%) | 132 (83.5%) | 0.653 (0.320-1.335) | p=0.241 |
OR, odds ratio; CI confidence interval.