Table 3.

Haplotype frequencies of three HMGB1 polymorphisms (rs1360485, rs1045411 and rs2249825) and risk of lung cancer.

Variable			Controls (N=758)n (%)	Patients (N=744)n (%)	OR (95% CI)	p value
rs1360485 A/G	rs1045411C/T	rs2249825C/G
A	C	C	571 (75.3%)	588 (79.0%)	Reference
G	T	G	97 (12.8%)	92 (12.4%)	0.921 (0.677-1253)	0.638
G	T	C	42 (5.5%)	21 (2.8%)	0.486 (0.284-0.830)	0.009*
G	C	C	27 (3.6%)	20 (2.7%)	0.719 (0.399-1.297)	0.3
A	T	C	13 (1.7%)	14 (1.9%)	1.046 (0.487-2.244)	1
G	C	G	4 (0.5%)	8 (1.1%)	1.942 (0.582-6.485)	0.386
A	C	G	2 (0.3%)	1 (0.1%)	0.486 (0.044-5.369)	0.62
A	T	G	2 (0.3%)	0 (0.0%)	-----