Figure 4.
Biodistribution of 64Cu-DOTA-Pab-IR800 and 64Cu-DOTA-IgG in mice bearing NCI/ADR-RES xenograft. Mice were injected with 64Cu-DOTA-Pab-IR800 and 64Cu-DOTA-IgG, and were sacrificed 48h post injection. Tissues and organs of interest were excised and weighed. Radioactivity was measured and the tracer uptake was calculated as %ID/g. The tumor uptake of 64Cu-DOTA-Pab-IR800 was significantly higher than that of 64Cu-DOTA-IgG at 48 h post injection