Table 2.

Characteristics of genetic variants associated with 25(OH)D concentration in published genome-wide association studies*

Single nucleotide polymorphism	Chromosome	Locus	Risk allele	β estimate†	P value
rs2282679	4	GC	G	−4.67	<3.4×10−302
rs10741657	11	CYP2R1	G	−1.72	6.5×10−81
rs12785878	11	DHCR7/NADSYN1	G	−2.11	6.4×10−129
rs6013897	20	CYP24A1	A	−0.98	3.4×10−17

*Source: Vimaleswaran, et al, 2013.²⁸

†Reported per unit change in nmol/L in natural scale per effect allele.