Patient selection diagram for candidates for STER at the Second Xiangya Hospital of Central South University (Changsha, China). *Gastric corpus or fundus proximate to the cardia, the lesser curvature of the gastric corpus and the greater curvature of the gastric antrum. #Ulceration or erosion at the tumor site; EUS reveals an irregular border, or internal heterogeneity, including an anechoic area (i.e. necrosis), echogenic loci (i.e. bleeding), heterogeneous enhancement or regional lymph node swelling; CT reveals metastasis or invasion out of the gastrointestinal tract; a Zubrod-Eastern Cooperative Oncology Group Performance Status ≥2; patient exhibits severe cardiopulmonary disease or blood coagulation disorders. SMT, submucosal tumor; CT, computerized tomography; EUS, endoscopic ultrasonography; MP, muscularis propria; STER, submucosal tunneling endoscopic resection.